Adderall is a combination medicine containing amphetamine and dextroamphetamine. It is generally well-tolerated and effective in treating the symptoms of ADHD and narcolepsy. At therapeutic doses, Adderall often causes emotional and cognitive effects such as euphoria, change in sex drive, increased wakefulness, and improved cognitive control. At these doses, Adderall induces physical effects such as fatigue resistance, a faster reaction time, and increased muscle strength.

In contrast, significantly higher amounts of Adderall can cause rapid muscle breakdown, impair cognitive control, provoke panic attacks, or induce a psychosis (e.g., hallucinations, paranoia, delusions). When given for ADHD, Adderall should be used in conjunction with other treatment strategies, such as psychotherapy, social integration advice, and education about the disorder. FDA has approved the use of Adderall in children over the age of three.

Clinical trials and medical uses of Adderall

Adderall is used to treat ADHD (or attention deficit hyperactivity disorder) and narcolepsy (a sleep disorder). Long-term amphetamine exposure at sufficiently large doses in some animal species produces abnormal dopamine system development or nerve damage. However, in humans with ADHD, pharmaceutical amphetamines appear to improve brain development and nerve growth at therapeutic dosages. Reviews of MRI or magnetic resonance imaging studies suggest that long-term treatment with amphetamine reduces brain function and structure abnormalities found in subjects with ADHD.

Adderall improves function in several parts of the brain, like the right caudate nucleus of the basal ganglia. Reviews of clinical stimulant research using Adderall have established the effectiveness and safety of long-term continuous amphetamine use for the treatment of ADHD. Two studies have suggested that long-term continuous stimulant therapy with Adderall for ADHD effectively reduces the significant symptoms of ADHD (i.e., inattention, hyperactivity, and impulsivity), enhancing the quality of life and academic achievement.

It also produces improvements in many functional outcomes across several categories of outcomes. These can be related to academics, antisocial behavior, driving, self-esteem, service use (i.e., academic, occupational, health, financial, and legal services), non-medicinal drug use, obesity, occupation, and social function.

How should I take Adderall?

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• Take this medication by mouth without or with food as directed by your doctor, usually one to three times a day.
• The first dose is generally taken as soon as you wake up in the morning.
• If more doses are prescribed, take them as directed by your doctor, usually four to six hours apart.
• You must take it at the same time each day for the best results.
• Adderall capsules should be swallowed whole with water or other liquids.
• If your child can not swallow the Adderall capsule, you can open it and sprinkle it over a spoonful of applesauce.

What should I know before buying Adderall online?

Adderall is an amphetamine. Amphetamines carry a risk of overdosage. Therefore, you must take the smallest amount possible to treat your condition. You must not take Adderall if you have:

• Glaucoma
• History of drug abuse
• History of agitated states
• Advanced arteriosclerosis
• Hypersensitivity to stimulants ( which may show up as anaphylaxis, severe skin rashes, or angioedema, which is quick swelling under the skin)
• Moderate to severe hypertension or bipolar disorder
• Hyperthyroidism
• Symptomatic cardiovascular disease

You must also avoid Adderall if you have taken MAOIs or monoamine oxidase inhibitors within the last 14 days. Extra caution must be warranted for people with certain underlying cardiovascular conditions, like recent heart attack, pre-existing hypertension, ventricular arrhythmia, or heart failure.

What is the half-life of Adderall?

Adderall has a half-life of about 9 to 14 hours, meaning that only half of the drug remains in your body after this period. Adderall usually clears a person’s system within 72 hours, but the half-life of Adderall may vary based on multiple factors.

Dosage of Adderall for ADHD

In children aged 6 to 12, this medication is usually started at Adderall 10 mg (milligrams) once daily and usually in the morning. The doctor can adjust the dosage of Adderall in increments of 5 or 10 milligrams at weekly intervals. There can be times when a physician decides to start the dosage at 5 milligrams once in the morning. The maximum recommended dose for children aged 6 to 12 is Adderall 30 mg per day. Doses higher than 30 milligrams per day have not been studied for their safety and efficacy in children. Adderall has not been researched in children below six years of age.

In adolescents with ADHD between 13 to 17 years, the recommended starting dose is 10 milligrams per day. After one week, the amount can be increased to 20 milligrams per day if their ADHD symptoms are not adequately managed and controlled.

In adults, the recommended dosage is 20 milligrams per day.

What are the side effects of Adderall?

• The side effects of Adderall differ widely among individuals but most commonly include dry mouth, loss of appetite, insomnia, and weight loss.
• The risk of developing a dependence or an addiction is insignificant when Adderall is used as directed at relatively low daily doses, like those used to treat ADHD. However, the routine usage of Adderall in larger daily amounts poses a significant risk of dependence or addiction because of the pronounced reinforcing effects that are present at large doses.
• Recreational doses of amphetamine are usually much larger than prescribed therapeutic doses and hence, carry a far greater risk of severe adverse effects.
• Adderall can also cause insomnia (inability to sleep), headache, dry mouth, loss of appetite, nervousness, and nausea.
• It may also cause heart palpitations, weight loss, changes in libido, constipation and other GI disturbances, alopecia (or hair loss), elevated blood pressure and muscle tightness, stiffness, or twitching.
• Reports indicate some temporary slowing of growth can occur when regular Adderall is given to children aged seven to ten years. Doctors must monitor the height and weight and consider treatment interruption if growth suppression is suspected.

Drug interaction of Adderall

Adderall can interact with the following substances: Adderall may increase the potency of tricyclic antidepressants and cause cardiovascular side effects. Antacids increase the absorption of Adderall, and one must avoid the use of antacids with Adderall. Acetazolamide and some thiazides raise blood levels of Adderall.